This chapter explores the devastating impact of repeated Israeli hostilities on Gaza, especially the recent war; October 2023–January 2025, on industry, innovation, and infrastructure in this region, focusing on the significant setbacks to achieving Sustainable Development Goal 9 (SDG 9). This brutal war has led to widespread destruction of critical infrastructure, including power plants, health facilities, and communication networks, crippling industrial activities and halting technological advancements. The destruction of manufacturing facilities and the scarcity of essential resources have severely limited production capabilities, leading to massive job losses and economic decline. Furthermore, the war has severely hindered the development of new technologies and innovations by destroying educational institutions and research centers, while restrictions on the import of technological equipment and resources have further exacerbated these challenges, limiting access to tools necessary for advancement and growth. Through detailed analysis of reports and scientific publications, this chapter highlights the urgent need for international intervention and support to rebuild industry and infrastructure in Gaza. This comprehensive examination of the impact of the war on Gaza industry, innovation, and critical infrastructure offers valuable insights into the broader challenges of achieving SDG 9 in conflict-affected regions.