Digital Twins (DT) are an emerging trend in diversified industrial sectors and their value chains. This study aims to explore current DT applications within SCs, focusing on sustainable inbound and outbound logistics and identifying key enablers that will facilitate the successful adoption of DTs in SCs. Using the PEO model and employing the PRISMA framework, this study screened articles from the Scopus database to explore the existing knowledge related to this topic. A steep increase in articles related to DTs over the past 10 years indicates that there is growing attention in exploring and leveraging this technology for various applications. The successful adoption of DTs is driven by several key factors, including advanced technological infrastructure; standardized processes; continuous improvement; knowledge workers; technologies like IoT, IIoT, AR/VR; and managerial support.