Disorders of the skin have been identified as skin diseases. These medical disorders may involve severe skin manifestations, including allergic reactions, frustration, and itching. Numerous skin disorders may be inherited, while other aspects may be caused by lifestyle. To diagnose the various skin disorders based on the symptoms of skin diseases, we introduce the novel idea of Interval-Valued T-Spherical Fuzzy Set (IV-TSFS) that significantly enhances the ability to handle vagueness and unpredictability in the data being gathered. The IV-TSFS takes the concept of T-SFS by incorporating Interval Values (IVs). This innovation greatly improves the capacity to represent and manage uncertainty because they offer a structured and flexible framework that captures real-world ambiguity, vagueness, and unpredictability as compared to other classical fuzzy models. In this article, we construct the extended conventional IV-TSF Evaluation based on Distance from Average Solution (EDAS) approach by using the conventional Evaluation based on Distance from Average Solution (EDAS) method and also identifying a wide range of possibilities and understanding the potential variability in outcomes, which is especially useful in Decision-Making (DM) scenarios. This method provides a balanced view of each alternative’s performance, helping decision-makers to rank and select the most suitable option effectively. It is the most powerful way to visualize and compare the performance of various alternatives in a structured and quantitative manner. Firstly, we briefly review the description of T-SFSs and IV-TSFSs and discuss the score function Ṩcr(₮), accuracy function Ἇcr(₮), and the basic Operational Laws (OLs) of IV-TSFVs. Next, we explain the extensive interventions of the extended conventional Interval-Valued T-Spherical Fuzzy (IV-TSF) EDAS method to cope with uncertain and unreliable information, which is especially useful in DM scenarios. Finally, a numerical example is provided to effectively diagnose the favorable skin disease based on the symptoms of skin diseases by using the IV-TSF EDAS approach, and several comparative results of our proposed model with other existing Aggregation Operators (AOs) are carried out to demonstrate the invaluable benefits associated with this strategy.