Introduction: A healthy fluid balance is necessary to maintain normal vital functions. Detecting the amount of body water is important both in clinical practice and in sports in assessing dehydration and/or fluid overload. Among the methods used to determine the amount and distribution of body water, devices operating on the principle of bioelectrical impedance are becoming more common. Their use is simple, fast and the results obtained are reliable. Objective: The aim of our study was to determine the relative body water content changing dependent on age in men and women of normal weight, overweight and obese, using a device that works on the principle of bioelectrical im¬pedance. Method: The data of a total of 2,354 persons between the ages of 7 and 81 are included in the study conducted with the InBody 720 type device. Normal body weight, overweight and obesity were determined using the body mass index. Results: There were significant differences between gender in body weight, body mass index between normal weight and overweight/obese participants in all age groups. The differences between relative body water content of men and women in normal body weight are significant in all age groups. The averages have not changed until the 3rd age group (21-50 years), then decreased in the 4th age group (above 51 years) in the normal body weight men. In thecase of normal body weight women, the averages decreased linearly dependent on age. The relative body water con¬tents in overweight/obese subjects were significantly lower by gender and age group than the averages of those with normal body weight. The relative water contents in overweight/obese men and women have not changed dependent on age. Discussion: Although bioelectrical impedance method is less commonly used, it is suitable for measuring total body water content. The reliability of the data obtained by the method is confirmed by more and more studies in the case of people of normal body weight, overweight and obese people as well. Conclusion: The bioelectrical impedance procedure can help prognosis and diagnosis in many areas. After presenting our data, we hope that our study will contribute to the spread of the bioelectrical impedance method.

Objectives: Data about coronary bifurcations treated with ultrathin strut drug-eluting stents (DES) using T-and-protrusion (TAP) technique is limited. Methods: In this study, a total of 84 consecutive patients, who underwent bifurcation percutaneous coronary intervention (PCI) with TAP technique using Orsiro® DES (Biotronik, Berlin, Germany), were included. All pre- and post-procedural data, as well as 1- and 2-year follow-up angiograms, were analyzed. Primary endpoints were procedural success and target lesion failure (TLF); secondary endpoints were all-cause mortality and major adverse cardiac and cerebrovascular events (MACCE) during follow-up. Results: Procedural success was achieved in 100% of cases. TLF rate was higher in patients presented with acute coronary syndrome compared to the ones with chronic coronary syndrome (19% vs. 5% p = 0.09). All-cause mortality was 30% during follow-up, from which 26% was due to non-cardiovascular cause, and the MACCE rate was 46%. Conclusions: Coronary bifurcations treated with ultrathin strut DES showed good short-term results and were associated with acceptable cardiovascular mortality. However, in these long-term patients, the rate of MACCE and non-cardiovascular death were rather high.

Purpose: Limited real-world data are available on the survival of patients treated with vitamin K antagonists (VKAs) versus with direct oral anticoagulants (DOACs) for nonvalvular atrial fibrillation (AF). In this nationwide registry, we analyzed the mortality risk of patients with nonvalvular AF taking DOACs versus VKAs, with a special attention to the early treatment period. Methods: The Hungarian National Health Insurance Fund (NHIF) database was searched to identify patients treated with VKA or DOAC as a thromboembolic prophylaxis for nonvalvular AF between 2011 and 2016. The overall and the early (0–3, 4–6, and 7–12 months) mortality risks with the 2 types of anticoagulation were compared. A total of 144,394 patients with AF treated with either a VKA (n = 129,925) or a DOAC (n = 14,469) were enrolled. Findings: A 28% improvement in 3-year survival with DOAC treatment compared with VKA treatment was shown. Mortality reduction with DOACs was consistent across different subgroups. However, younger patients (30–59 years old) initiated on DOAC therapy had the greatest RRR (53%) in mortality. Furthermore, DOAC treatment also yielded a benefit of greater magnitude (HR = 0.55; 95% CI, 0.40–0.77, P = 0.001) in the lower (0-1) CHA2DS2-VASc score segment and in those with fewer (0–1) bleeding risk factors (HR = 0.50, CI 0.34–0.73, P = 0.001). The RRR in mortality with DOACs was 33% within the first 3 months, and 6% in the second year. Implications: Thromboembolic prophylaxis with DOACs in this study yielded significantly lower mortality compared with VKA treatment in patients with nonvalvular AF. The largest benefit was shown in the early period after treatment initiation, as well as in younger patients, those with a lower CHA2DS2-VASc score, and those with fewer bleeding risk factors.

Introduction: Morbidity and mortality statistics show a shift in the morbidity structure in Hungary. Those diseases have become increasingly common that are related to lifestyle. Detecting health risk factors across different age, gender and other groups is therefore a priority. Objective: The purpose of the study is to present anthropometric variables related to the health status of male physical workers by age groups and to identify critical age stages. Method: Male manual workers (n = 179) were recruited on a voluntary basis. Body composition was assessed using the Inbody 720 instrument. Measured and calculated characteristics included body mass index, relative muscle and fat mass, waist-to-hip ratio and visceral fat. The age dependence of the variables is presented by linear regression analysis, and the relationship between variables was characterized by correlation coefficients. Results: A significant number of anthropometric variables are not within the healthy range. All of the variables show age dependence, but no critical age or age range could be identified. The relationship between the anthropometric methods is significant. Discussion: A large number of male manual workers, regardless of age, can be identified as having a body composition that poses a clear health risk. Conclusion: Complex workplace health promotion programs should be launched to reduce the risk. These should include active and health-conscious lifestyles for all age groups.

Introduction: Professionals working in the social sector typically do significant overwork in rather unfavourable working conditions. Although the purpose in life is proved to determine the areas of career, health awareness, and the quality of life, the latter has not yet been confirmed among social workers. Objective: The purpose of this research is to demonstrate body composition and fitness status as well as the quality of life of female employees (n = 127) at a social institution, furthermore the decisive role purpose of life plays in these indicators. Method: Data were collected through questionnaires, tests, body composition analyses, and fitness status tests, and were assessed by t-test, analysis of variance and regression analysis. Results: Body composition of the participants indicates a generally overweight status, while fitness status, quality of life, and purpose of life are within the acceptable range, however, all with notable range values. Those with a higher-level purpose of life demonstrate better fitness indicators and higher quality of life. In terms of body composition, fitness, and quality of life, only a minor difference was found between those who do intellectual and physical type of work. Those who took sick leave demonstrated a lower level of fitness and quality of life compared to those who did not take any sick leave. Body composition and fitness status have proven to deteriorate with age. Conclusion: Previous research findings can be confirmed by stating that neither the body composition and fitness indicators, nor the quality-of-life level of social workers are optimal. The determining role of purpose in life has been proven in substantial aspects in this study. One of the focus areas of enhancing purpose in life is the workplace, where major positive impacts can be achieved in terms of the physical and mental health, well-being, and work performance.