This study examines the impact of long-term relationships and vendor-managed inventory on supply chain performance and the mediating role of information sharing in Pakistan’s textile industry. For testing the proposed hypotheses of the present study, the primary data was gathered with the help of a questionnaire from past studies via a convenience sampling strategy. Three hundred fifty questionnaires were distributed among the textile industry through the HR department of the concerned firm. However, only 330 cases were considered for data analysis after data clearing in SPSS version 25. Hence, the response rate is 94%. The data were analysed using SEM in Smart-PLS version 3. The results of hypothesis testing indicated the direct effect of long-term relationships and vendor-managed inventory, which was found to have a positive and significant impact on information sharing and supply chain performance in Pakistan’s textile industry. Furthermore, the mediating effect of information technology between long-term relationships and vendor-managed inventory revealed a partial mediation effect on supply chain performance. The policymakers and top management of concerned firms should consider these variables for future strategies to get better supply chain performance.