Today, the discourse around the current issues of effective learning is increasingly centred on modern information and communication technologies (ICT) and artificial intelligence (AI)-based methodological and technological solutions. ICT tools, such as online learning platforms, virtual classrooms and digital textbooks, have significantly transformed the educational environment, providing opportunities for personalised learning and remote access. In addition, AI-based applications, such as student performance analysis and curriculum customisation, are opening up new horizons in education. AI can create adaptive learning systems that continuously adapt to the needs and progress of students, thus increasing the effectiveness of learning. But these new technologies and methods also bring with them a number of challenges. One major challenge is digital inequality, as not all students have access to ICT tools and the Internet. Furthermore, educators need to continuously develop their digital competences to keep up with technological developments and effectively integrate new methods into teaching. There are also ethical issues, in particular data protection and student privacy. New opportunities include the use of learning analytics to help educators better understand learning processes and identify areas where students need help. Interactive and gamified learning materials developed with the help of AI can make learning more motivating and enjoyable, thereby increasing student engagement. Overall, the integration of modern ICT and AI-based methods and technologies into education offers significant benefits, but their successful implementation requires adequate infrastructural support, continuous training for teachers and digital access for students. This article provides a brief summary of all these phenomena, trends, opportunities and good practices.