Meriem Boukhiam
59904024100
Publications - 1
Global, regional, and national burden of headache disorders, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
Sharareh Eskandarieh
Andre Faro
Giuseppina Affinito
Yaser Mohammed Al-Worafi
Abhishek Anil
Mohammad Amin Aalipour
Dariush Abtahi
Hiba Jawdat Barqawi
Danish Ahmad
Syed Shujait Ali
Karem H. Alzoubi
Yasser Bustanji
Salahdein Aburuz
Khursheed Aurangzeb
Qorinah Estiningtyas Sakilah Adnani
Deldar Morad Abdulah
Qorinah Estiningtyas Sakilah Adnani
Richard Gyan Aboagye
Jalal Arabloo
Mohammad Mahdi Bastan
Sonu Bhaskar
Mohammad Al-Wardat
Ganiyu Adeniyi Amusa
Demelash Areda
Mahsa Asadi Anar
Sait Ashina
Joseph Uy Almazan
Ashraf Alhumaidi
Mohammad Ahmmad Mahmoud Al Zoubi
Negar Sadat Ahmadi
Andreas Kattem Husøy
Yvonne Yiru Xu
Jaimie D. Steinmetz
Samir Abu Rumeileh
Ali Ahmed
Sawsan Alabbad
Yazan Al-Ajlouni
Obed Adonteng-Kissi
Gelana Fekadu
Hasan Aalruz
Jasvinder Singh Bhatti
C. J. Sanjay
Natalia Cruz-Martins
Edoardo Caronna
Ana Paula Carvalho-E-Silva
Jeetendra Bhandari
Bijit Biswas
Aleksandr Y. Aravkin
Omid Dadras
Hongyuan Chu
Josielli Comachio
Arian Azadnia
Youngoh Bae
Rehana Basri
Jina Behjati
Daniela Contreras
Gurjit Kaur Bhatti
Rajbir Bhatti
Emanuele D'Amico
Anh Kim Dang
Lucio D'Anna
Bruno Bizzozero-Peroni
Meriem Boukhiam
Sindhura Deekonda
Pouria Delbari
Andreas K. Demetriades
Emina Dervišević
Lamiaa Labieb Mahmoud Ebraheim
Ebrahim Eini
Michael Ekholuenetale
Vinoth Gnana Chellaiyan Devanbu
Mohammad Asghari-Jafarabadi
Razieh Bahreini
Bibha Dhungel
Maryam Bemanalizadeh
Mohammed Albashtawy
Fadwa Naji Alhalaiqa
Joseph Uy Almazan
Sohrab Amiri
Asma Ahmed
Montaha Al-Iede
David B. Anderson
C. J. Sanjay
Natalia Cruz-Martins
Valery L. Feigin
Awais Altaf
Ahmed Y. Azzam
Mohammed Usman Ali
Najim Z. Alshahrani
Soham Bandyopadhyay
Xueting Ding
Huyen Phuc Do
Ojas Prakashbhai Doshi
Siddhartha Dutta
Sandip Chakraborty
Luis Alberto Cámera
Azadeh Bashiri
Vijay Kumar Chattu
Amol S. Dhane
Archith Boloor
Patrick R. Ching
Xiaochen Dai
Anis Ahmad Chaudhary
Shahzaib Ahmed
Publication Name: Lancet Neurology
Publication Date: 2025-12-01
Volume: 24
Issue: 12
Page Range: 1005-1015
Description:
Background: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2023 estimates health loss from migraine, tension-type headache, and medication-overuse headache. This study presents updated results on headache-attributed burden from 1990 to 2023, along with clinical and public health implications. Methods: Data on the prevalence, incidence, or remission of migraine, tension-type headache, and medication-overuse headache were extracted from published population-based studies. We used hierarchical Bayesian meta-regression modelling to estimate global, regional, and country-level prevalence of headache disorders. For the first time in GBD 2023, age-specific and sex-specific estimates of time in symptomatic state were applied by meta-analysing individual participant data from 41 653 individuals from the general populations of 18 countries from all parts of the world. Disability weights were applied to calculate years lived with disability (YLDs). Since medication-overuse headache is a sequela of a mistreated primary headache (due to medication overuse), its burden was reattributed to migraine or tension-type headache, informed by a meta-analysis of three longitudinal studies. Findings: In 2023, 2·9 billion individuals (95% uncertainty interval 2·6–3·1) were affected by headache disorders, with a global age-standardised prevalence of 34·6% (31·6–37·5) and a YLD rate of 541·9 (373·4–739·9) per 100 000 population, with 487·5 (323·0–678·8) per 100 000 population attributed to migraine. The prevalence rates of these headache disorders have remained stable over the past three decades. YLD rates due to headache disorders were more than twice as high in females (739·9 [511·2–1011·5] per 100 000) as in males (346·1 [240·4–481·8] per 100 000). Medication-overuse headache contributed 58·9% of the YLD estimates for tension-type headache in males and 56·1% in females, as well as 22·6% of the YLD estimates for migraines in males and 14·1% in females. Interpretation: Headache disorders, in particular migraine, continue to be a major global health challenge, emphasising the need for effective management and prevention strategies. Much headache-attributed burden could be averted or eliminated by avoiding overuse of medication (including over-the-counter medication), underscoring the importance of public education. Funding: Gates Foundation.
Open Access: Yes
