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Found 5157 publications
Montelukast Improves Urinary Bladder Function After Complete Spinal Cord Injury in Rats
Publication Name: International Journal of Molecular Sciences
Publication Date: 2025-06-01
Volume: 26
Issue: 12
Page Range: Unknown
Description:
Bladder dysfunction is among the most drastic and quality-of-life-reducing conditions after spinal cord injury (SCI). Neuroinflammation in the lower urinary tract (LUT) after SCI could be a key driver of neurogenic bladder dysfunction and tissue fibrosis. Leukotrienes, a group of highly active lipid mediators, are potent inflammatory mediators. Here, we explored the potential of early montelukast (MLK) therapy, a cysteinyl leukotriene receptor 1 antagonist, on LUT function and structure four weeks after severe SCI in rats. Rats (strain Lewis, female, n = 50) received a permanent bladder catheter, followed by a complete T9 spinal cord transection. MLK was given daily, starting on day one post-injury. Bladder and locomotor function were regularly assessed. Bladder tissue was histologically and immunhistochemically analyzed. Post-SCI, MLK concentrations in plasma and cerebrospinal fluid were clinically relevant. MLK improved bladder functionality. MLK had no impact on smooth muscle alignment and uroepithelial integrity at this early SCI time point. This pilot study gave first insights into early, continuous oral MLK treatment with the first promising results of preserved LUT function and possible subsequent improved tissue integrity.
Open Access: Yes
DOI: 10.3390/ijms26125606
A structured framework for HBIM standardization: Integrating scan-to-BIM methodologies and heritage conservation standards
Publication Name: Digital Applications in Archaeology and Cultural Heritage
Publication Date: 2025-06-01
Volume: 37
Issue: Unknown
Page Range: Unknown
Description:
Heritage conservation demands innovative approaches that integrate advanced technologies with traditional principles to protect monuments and historic buildings. This research investigates the potential of Building Information Modeling (BIM) in heritage conservation, with a focus on developing and adapting workflows tailored to Heritage Building Information Modeling (HBIM). Through a systematic analysis of literature, the research highlights the adaptation of scan-to-BIM methodologies for HBIM creation and their significant role in enhancing preservation efforts. Key technologies, including laser scanning, photogrammetry, and machine learning, are discussed for their contributions to generate accurate and information-rich digital models of heritage structures. Furthermore, this work discovers critical specifications and proposes a structured framework for balancing these specifications within HBIM workflows. This framework addresses challenges such as standardization, scalability, and adaptability, which are essential for accurately capturing the complexity of heritage buildings. By examining these issues, the study identifies opportunities to improve HBIM's capability to monitor, document, and manage culturally significant assets. The findings provide a comprehensive understanding of HBIM processes and their potential to support the effective conservation of heritage.
Open Access: Yes
The nexus of IoT and aquaculture: A bibliometric analysis
Publication Name: Applied Food Research
Publication Date: 2025-06-01
Volume: 5
Issue: 1
Page Range: Unknown
Description:
The Internet of Things (IoT) in aquaculture presents significant opportunities for improving the sector's productivity, sustainability, and resilience. This study aims to achieve two primary goals: to deliver an extensive overview of IoT applications in aquaculture and to pinpoint emerging trends and research gaps, thereby directing future academic endeavors in the aquaculture field. Through bibliometric analysis, which involved keyword co-occurrence and article co-citation network analyses, we investigated 428 publications from 2012 to 2024 retrieved from Scopus. The review indicates a significant rise in investigative efforts, especially in recent years, highlighting the sector's increasing focus on the role of IoT in tackling the distinct challenges aquaculture faces, including water quality monitoring, disease prevention, and resource efficiency. Prominent themes recognized encompass advanced aquaculture systems, water quality and health monitoring, and sophisticated forecasting tools. This investigation enhances the existing knowledge base by emphasizing key themes, significant studies, and essential technological advancements in IoT-enabled aquaculture, providing one of the initial bibliometric assessments in this swiftly developing field. Future research should focus on enhancing interoperability among IoT devices, improving data security and privacy, integrating artificial intelligence for predictive analytics, and expanding IoT applications to support small-scale and resource-constrained aquaculture operations.
Open Access: Yes
The influence of hybrid leadership in sustainable women entrepreneurial performance
Publication Name: Sustainable Futures
Publication Date: 2025-06-01
Volume: 9
Issue: Unknown
Page Range: Unknown
Description:
In the contemporary era, strategic leadership style plays significant role in entrepreneurial performance. The key purpose of this study is to examine the influence of hybrid (self, shared and opinion) leadership in women entrepreneurial performance towards sustainable growth. This mixed method study investigated data in two ways. First, the study analyzed the data and measured the hypotheses employing the partial least squares structured equation model (PLS-SEM) in SmartPLS software 4 packages. Second, fsQCA explores multiple causal relationships between the constructs. The fsQCA results claim that the multiple causal relationships among the shared, self and opinion leadership have strong significant impact on women entrepreneurial performance. In particular, it is addressed that different entrepreneurial performances are positively associated with the extent of self, shared and opinion leadership. Theoretically, this study contributes to the understanding of women leadership behavior in entrepreneurial performance with a mixed statistical analysis. The study has valuable insights for the women entrepreneurs and concerned
Open Access: Yes
Development of Magnetic Hysteresis Loop Measurement System for Characterization of 3D-Printed Magnetic Cores
Publication Name: Electronics Switzerland
Publication Date: 2025-06-01
Volume: 14
Issue: 11
Page Range: Unknown
Description:
Today, numerous advanced options exist for analyzing and measuring magnetic hysteresis loops and core loss across a broad spectrum of applications. Most of these systems are compact and ready to use, fulfilling the measurement and data processing requirements for laminated iron cores according to the standards. However, modeling newly developed materials with complex structures or the high-frequency behavior of iron cores, and the computation of dynamic hysteresis properties’ temperature dependence, are still challenging problems in the field. Moreover, these standardized measurement tools are relatively expensive, and most of them represent a black box that impedes research and further development. This paper presents the development of a cheap and accessible measurement system that is explicitly designed for recording the hysteresis properties of 3D-printed iron cores. The paper presents a comprehensive overview of the design process, components, circuitry, and simulations integral to this project. The paper presents a completed circuit simulation conducted using LTspice and validation of the prototype’s measurement performance. The measurements obtained with the proposed system show good agreement with those of the reference setup, demonstrating its accuracy and practical applicability.
Open Access: Yes
Microalgae–bacteria interaction: a catalyst to improve maize (Zea mays L.) growth and soil fertility
Publication Name: Cereal Research Communications
Publication Date: 2025-06-01
Volume: 53
Issue: 2
Page Range: 1037-1049
Description:
Biofertilisers harbouring living organisms hold allure due to their prospective favourable influence on plant growth, coupled with a diminished environmental footprint and cost-effectiveness in contrast to conventional mineral fertilisers. The purpose of the present study was to evaluate the capacity of a specific microalga (MACC-612, Nostoc linckia) biomass and plant growth-promoting bacteria (PGPB) separately and together to improve crop growth and promote soil health. The research used a factorial design within a completely randomised block framework, featuring four replications for three consecutive years across different fields. The experiment utilised three levels of microalga (control, 0.3 g/L of N. linckia, MACC-612, and 1 g/L of N. linckia, MACC-612) and three levels of bacterial strains (control, Azospirillum lipoferum and Pseudomonas fluorescens). The result demonstrated that the use of N. linckia and PGPB separately or jointly as soil treatment resulted in a substantial improvement in chlorophyll, plant biomass, soil humus, and nitrogen, depending on the environmental conditions of the years. The combined use of N. linckia and PGPB results in an improvement in dry leaf weight by 35.6–107.3% at 50 days after sowing (DAS) and 29.6–49.8% at 65 DAS, compared to the control group. Furthermore, the studies show that the synergistic application of N. linckia at 0.3 g/L, in conjunction with A. lipoferum, significantly improved total nitrogen and (NO3 − + NO2 −)-nitrogen, registering increases of 20.7–40% and 27.1–59.2%, respectively, during the study period. The most effective synergistic combination was identified through the application of 0.3 g/L of N. linckia along with A. lipoferum. Hence, application of biofertilisers through synergistic combinations of two or more microorganisms, such as microalgae and bacteria, holds promise in improving crop chlorophyll, growth, and soil nitrogen.
Open Access: Yes
The effects of environmental factors on the embryonic and late postembryonic life through epigenetic mechanisms
Publication Name: Orvosi Hetilap
Publication Date: 2025-05-25
Volume: 166
Issue: 21
Page Range: 799-807
Description:
It has long been known that, in addition to genetic factors, epigenetic effects fundamentally influence the functioning of the living organism. Although the genome of individual cells of the human body is almost identical, the access, transcription and expression of genetic information are influenced by epigenetic effects. The eukaryotic nuclear DNA is wrapped around histone octamers to form the nucleosome, the basic unit of the chromatin structure. The covalent modifications of the histone proteins cause epigenetic changes. Human conception, followed by the division and implantation of the fertilized egg into the maternal decidua, is a complex process that requires the coordinated functioning of embryological, immunological processes and anatomical structures. The steps of these processes are genetically determined and the coarse- and fine-tuning of these effects occurs at the epigenetic level by external effects such as hormones, toxins, changes in diet, infections, or cell differentiation. The most significant rearrangements occur in the embryonic period after the fertilization of the egg. In our paper, we review the literature to present the effects that influence the fine-tuning of genome function at the epigenetic level. Disturbances of these mechanisms are the basis of several pathologies that threaten conception, implantation and successful pregnancy, such as recurrent miscarriage, preeclampsia, fetal growth restriction or premature birth. In addition, epigenetic alterations acting during the period of plasticity of individual development can cause diseases that appear in the young, adult and even old age of the offspring, which can even be inherited through generations.
Open Access: Yes
Contribution to knowledge of the oribatid mite genus Achipterina (Acari, Oribatida, Ceratokalummidae)
Publication Name: International Journal of Acarology
Publication Date: 2025-05-19
Volume: 51
Issue: 4
Page Range: 251-257
Description:
Achipterina (Oribatida, Ceratokalummidae) currently comprises four species, collectively distributed in the tropical and subtropical areas. We describe a new species—A. mangrovicasp. nov.—based on adults collected from litter of a mangrove forest in the Can Gio Biosphere Reserve, southern Vietnam. It is the first representative of the family discovered in the Vietnamese fauna. The new species is characterized in having a bidentate rostrum, setiform rostral and lamellar setae, long inner tooth of lamellar cusp, unilaterally fusiform bothridial seta, long interlamellar seta, dentate anterior part of pteromorph, oval and oblique notogastral porose area Aa. The morphology of the gnathosoma, ovipositor, and legs are presented for the first time for Achipterina. An identification key and summary of distribution and habitats of the known species of Achipterina are provided. http://www.zoobank.org/urn:lsid:zoobank.org:pub:906EA4DE-A0A3-475C-B273-F8327F44832F.
Open Access: Yes
Comparison of some economic traits by genetic cluster of Aberdeen Angus cattle
Publication Name: Archives Animal Breeding
Publication Date: 2025-05-12
Volume: 68
Issue: 2
Page Range: 279-286
Description:
The Angus cattle population of Hungary was categorized into four groups using 12 microsatellite markers exhibiting notable genetic variations. Moreover, some traits influencing the profitability and sustainability of beef cattle farming were compared between groups. Data were obtained from 5075 cows (born between 1990-2020) and 19 142 calves (born between 1997-2023), including 10 629 bull calves and 8513 heifer calves of different genetic backgrounds. Genetic groups were distinguished by origin, color, size, and type: blue group (BG), red group (RG), green group (GG), and yellow group (YG). The six investigated traits were age at first calving (AFC), productive lifespan (PL), number of calves born (NCB), culling age (AGE), birth weight (BW), and the 205 d adjusted weaning weight (WW). The averages of the six tested traits were as follows: AFC - 2.35 ± 0.54 years; NCB - 5.89 ± 3.69 heads; PL - 6.85 ± 4.13 years; AGE - 9.2 ± 4.26 years; BW - 29.4 ± 4.28 kg; and WW - 176.9 ± 44.07 kg. YG excelled in terms of NCB, PL, AGE, and WW traits, while RG performed best in terms of AFC and BW. BG displayed the lowest performance across NCB, PL, AGE, BW, and WW. The heavier Red Angus individuals were largely behind the performance of the traditional-type, smaller British-type Black and Red Angus individuals in the tested traits affecting sustainability and profitability. Significant reproduction and longevity trait differences exist among different genetic groups of Angus beef cattle genotyped by DNA microsatellite information. The results indicated significant differences in terms of the performance of different Angus types with regard to the tested traits. These findings could be useful in developing breeding concepts and making selection decisions, contributing to more efficient and sustainable breeding strategies.
Open Access: Yes
