Chuanhua Yu

57208140344

Publications - 2

Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: a Global Burden of Disease Study

Muhammad Suleman Masood Ali Shaikh Jiseung Kang Sa’ed H. Zyoud Chuanhua Yu Naohiro Yonemoto Manish Vinayak Georgios Ioannis Verras Siavash Vaziri Hyeon Jin Kim Min Seo Kim Magdalena Zielińska Bin Zhu Paul Yip Dehui Yin Renjulal Yesodharan Tommi Juhani Vasankari Joe Varghese Jef Van den Eynde Munkhtuya Tumurkhuu Abdul Rohim Tualeka Evangelia Eirini Tsermpini Aristidis Tsatsakis Alexander C. Tsai Samuel Joseph Tromans Atta Ullah Masayuki Teramoto Mohamad Hani Temsah Reem Temsah Yonas Getaye Tefera Minale Tareke Vinay Suresh Vetriselvan Subramaniyan Dan J. Stein Chandrashekhar T. Sreeramareddy Ireneous N. Soyiri Joan B. Soriano Soroush Soraneh Roman Shrestha Sunil Shrestha Pavanchand H. Shetty Premalatha K. ShettyS Seyed Afshin Shorofi Aminu Shittu Ujjawal Sharma Manoj Sharma Javad Sharifi Rad Amin Sharifan Alfiya Shamsutdinova Sunder Sham Anthony Zhong Jingya Zhang Haijun Zhang Mohammed G.M. Zeariya Aurora Zanghì Fathiah Zakham Hadiza Yusuf Zwanden Sule Yahaya Marcos Roberto Tovani-Palone Marco Torrado Jovana Todorovic Tenaw Yimer Tiruye Kavumpurathu Raman Thankappan Ker Kan Tan Baljinder Singh Jasvinder A. Singh Luís Manuel Lopes Rodrigues Silva João Pedro Silva Inga Dora Sigfusdottir Emmanuel Edwar Siddig Mahabalesh Shetty Ali Sheidaei Vishal Sharma Angga Wilandika Asokan Govindaraj Vaithinathan Shu Wang Nuwan Darshana Wickramasinghe Yuan Pang Wang Mandaras Tariku Walde Isidora S. Vujcic Saeed Ullah Aniefiok John Udoakang Thang Huu Tran Nguyen Tran Minh Duc Mircea Tampa Seyyed Mohammad Tabatabaei Rafael Tabarés-Seisdedos Payam Tabaee Damavandi Lukasz Szarpak Chandan Kumar Swain Matiwos Soboka Mehran Shams-Beyranvand Alireza Shakeri Masood Ali Shaikh Y. Waheed Farrukh Sobia Anna Aleksandrovna Skryabina Valentin Yurievich Skryabin Surjit Singh Harmanjit Singh Paramdeep Singh Sa’ed H. Zyoud Asokan Govindaraj Vaithinathan Shu Wang Pavanchand H. Shetty Marco Torrado Premalatha K. ShettyS

Publication Name: Nature Medicine

Publication Date: 2026-02-01

Volume: 32

Issue: 2

Page Range: 527-544

Description:

Drug use disorders (DUDs) are emerging global public health challenges. Here we investigated the global and regional estimates of the prevalence and burden of DUDs, including amphetamine, cannabis, cocaine and opioid use disorders, from 1990 to 2023 for 204 countries and territories by using the Global Burden of Disease Study 2023. Overall, trends in global age-standardized disability-adjusted life-years of DUDs increased from 169.3 (95% uncertainty interval (95% UI), 134.4–203.9) per 100,000 people in 1990 to 212.0 (95% UI, 179.2–245.6) in 2023. In 2023, both prevalence and burden of DUDs were higher in high-income countries, particularly in the USA. The most prevalent DUDs in 2023 were cannabis use disorder (age-standardized prevalence, 270.8 (95% UI, 201.7–350.0) per 100,000 people) and opioid use disorder (205.9 (95% UI, 178.7–235.0)). Particularly, opioid use disorder showed a nearly twofold increase in prevalence and burden between 1990 and 2023. In 2023, compared with countries where cannabis use was illegal, countries permitting both recreational and medical cannabis use had higher prevalence rates for all types of DUDs. Proactive and effective policies are essential to mitigate the increasing global burden of DUDs.

Open Access: Yes

DOI: 10.1038/s41591-025-04137-0

Global, regional and national burden of ischemic heart disease attributable to suboptimal diet, 1990–2023: a Global Burden of Disease study

Marcin W. Wojewodzic Dinesh Upadhya Ahmed Bilal Waqar Kazumasa Yamagishi Zhiyong Zou Y. Waheed Suowen Xu Abdul Rohim Tualeka Dakshitha Praneeth Wickramasinghe Mircea Tampa Nuwan Darshana Wickramasinghe Rasiah Thayakaran Felicia Wu Rajshree Thapa Pugazhenthan Thangaraju Dehui Yin Isidora S. Vujcic Galal Yahya Mohamad Hani Temsah Yunquan Zhang Shoban Babu Varthya Muhammad Umair Marcos Roberto Tovani-Palone Domenico Trico Casper J. P Zhang Madhur Verma Aurora Zanghì Xiao Dong Zhou Dong Keon Yon Bin Zhu Nguyen Tran Minh Duc Habib Yaribeygi Mohammed Zawiah Jibrin Sammani Usman Tommi Juhani Vasankari Loc Tri Vu Peter Willeit Dominique Vervoort Pengpeng Ye Kavumpurathu Raman Thankappan Dipan Uppal Min Seo Kim Ramna Thakur Anggi Lukman Wicaksana Naohiro Yonemoto Stefanos Tyrovolas Chuanhua Yu Yuichi Yasufuku Zenghong Wu Andrea Werdecker Khaled Trabelsi Mary Njeri Wanjau Jacques Lukenze Tamuzi Shuduo Zhou Nguyen Tran Minh Duc Aniefiok John Udoakang Haosu Tang Sojit Tomo Lakshmi Thangavelu Ghazal Zoghi Masayuki Teramoto Toyiba Hiyaru Wassie Georgios Ioannis Verras Joe Varghese Subah Abderehim Yesuf Nathan Y. Tat Anthony Zhong Zhiqiang Zhang Abzal Zhumagaliuly Thang Huu Tran Manish Vinayak Thien Tan Tri Tai Truyen Asokan Govindaraj Vaithinathan Sa’ed H. Zyoud Magdalena Zielińska Asokan Govindaraj Vaithinathan Krishna Tiwari Jansje Henny Vera Ticoalu Nghia Minh Tran Munkhtuya Tumurkhuu Quynh Thuy Huong Tran Jef Van den Eynde Yanzhong Wang Xiaoyue Xu Mohammed Y. Youssef Wanqing Xie Xingxin Wang Hanqing Zhao Yuichiro Yano Yihun Miskir Wubie Claire Chenwen Zhong Salih M.Mustafa Salih Zebari Sa’ed H. Zyoud Yuichi Yasufuku Lakshmi Thangavelu Tewodros Eshete Wonde Rekha Thapar Xing Wang Casper J. P Zhang Liqun Zhang Mohammed G. M Zeariya Era Upadhyay Ali H. Mokdad Marcello Tonelli Iman M. Talaat Mathilde Touvier

Publication Name: Nature Medicine

Publication Date: 2026-04-01

Volume: 32

Issue: 4

Page Range: 1454-1478

Description:

Ischemic heart disease (IHD) remains a leading cause of death worldwide, with dietary risks being its most significant modifiable factor. Here, using the Global Burden of Diseases, Injuries and Risk Factors Study 2023, we estimated the mortality and disability-adjusted life years from diet-related IHD across 204 countries. In 2023, a suboptimal diet was responsible for 4.06 million (95% uncertainty interval (UI) 0.74–6.22) IHD deaths and 96.84 million (18.82–142.52) IHD disability-adjusted life years. The global age-standardized death rate of IHD attributable to suboptimal diet decreased by 43.92% (95% UI 34.44–53.23) per 100,000 population from 1990 to 2023. Among dietary factors, low intake of nuts and seeds (9.87, 95% UI 2.84–17.12 deaths per 100,000 population), low whole grains (9.22, 4.73–13.67), low fruits (7.25, 1.54–13.34) and high sodium (7.15, 0.92–17.97) were primary contributors to IHD deaths. The burden was particularly pronounced in low- and middle-sociodemographic index countries. By disentangling dietary risk factors, we identified the portion of IHD burden directly modifiable through food interventions.

Open Access: Yes

DOI: 10.1038/s41591-026-04250-8