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Authors - 9551
Gabor Kovacs
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László Nádai
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Erzsébet Háznagy-Radnai
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Xi Wang
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Publications - 6278
Placebo and nocebo interventions impact perceived but not actual proprioceptive accuracy
Publication Name: Plos One
Publication Date: 2024-08-01
Volume: 19
Issue: 8
Page Range: Unknown
Description:
Changes in performance caused by positive and negative expectations (i.e., placebo and nocebo responses) were found to play an important role in many aspects of motor performance. This study aimed to test the impact of placebo/nocebo responses and the assumed moderating role of dispositional optimism and anxiety on proprioceptive accuracy, an essential aspect of motor functions. 78 undergraduate university students completed questionnaires assessing dispositional optimism, state anxiety, and motivation to cooperate, then were randomly assigned to three experimental groups. A sham subliminal electric stimulation was applied with claimed positive (placebo group, n = 26), negative (nocebo group, n = 26) or neutral (control group, n = 26) impact on proprioceptive accuracy. Proprioceptive accuracy was measured with active and passive versions of the Joint Position Reproduction task before and after the intervention. Expected and perceived changes in performance were also assessed; changes in state anxiety, optimism, and motivation to cooperate were used as control variables (covariates). Mixed analyses of variance indicated that the experimental manipulation did not affect actual proprioceptive accuracy but impacted expected and perceived performance. Adding the covariates to the models did not substantially change the results. Further, no significant association emerged between actual and perceived change in performance in the active test, and only a weak correlation was found in the passive test. Expected performance did not predict actual performance but predicted perceived performance in both tasks. The results suggest that only perceived (subjective) aspects of proprioceptive accuracy are susceptible to placebo and nocebo interventions.
Open Access: Yes
The P-graph application extension in multi-period P2P energy trading
Publication Name: Renewable and Sustainable Energy Reviews
Publication Date: 2024-08-01
Volume: 200
Issue: Unknown
Page Range: Unknown
Description:
An optimization model that incorporates all combinatorically feasible inter-plant collaboration networks is developed using P-graph. It has been theoretically proven that time-sliced-based energy planning optimization has positive impacts and is capable of achieving carbon emissions reduction goals and minimizing costs simultaneously. However, as the number of entities increased, an exponential growth in possible combinatorial feasible coalitions is anticipated. Therefore, an extension of the P-graph optimization tool that is capable of generating all possible outcomes in multi-period P2P energy trading – PEP (P-graph for energy planning) is developed. The PEP software can be effectively used in modelling complex process networks graphically and solving optimization problems with the combined advantages of combinatorial algorithms and mathematical programming. In this paper, a systematic framework for implementing P2P energy trading using PEP software is proposed and demonstrated using a real-life case study.
Open Access: Yes
Adaptation of road safety inspection method to railway level crossings
Publication Name: Pollack Periodica
Publication Date: 2025-03-26
Volume: 20
Issue: 1
Page Range: 39-45
Description:
In recent years, the number of road traffic crashes showed a decreasing trend in Hungary, but this cannot be stated about crashes at road-railway level crossings. The Hungarian Railways has repeatedly called attention to the dangers of rail transport. The main goal of this paper is to develop a new safety inspection method for road-railway level crossings based on the existing road safety inspection method. Based on the experiences of road safety inspections completed at ten locations suggestions were given for the adaptation of the method to railway crossings. The most important findings of the safety inspections are also presented in the paper.
Open Access: Yes
The Impact of LED-Based eHMIs on Pedestrian Decision-Making and Perceptions at Crossings
Publication Name: Transportation Research Procedia
Publication Date: 2025-01-01
Volume: 91
Issue: Unknown
Page Range: 163-170
Description:
Effective communication between vehicles and pedestrians is essential for ensuring crossing safety, particularly as automated vehicles (AVs) become more prevalent. This study evaluated pedestrian perceptions of five communication scenarios using green LED-based External Human–Machine Interfaces (eHMIs) mounted on a conventional vehicle: (A) an arrow LED on the license plate, (B) an arrow LED on the windscreen, (C) a full LED on the license plate, (D) a full LED on the windscreen, and (E) no LED interface (control). Participants viewed video recordings of each scenario and responded to questions regarding perceived safety, clarity, and trust. Additionally, their leg movement onset time was recorded as an indicator of crossing decision behavior. The results indicated that the full LED on the license plate was perceived as the most trustworthy and clear, and it elicited faster crossing decisions compared to the control condition. In contrast, no LED interface yielded the lowest scores for clarity, safety, and trust, and was associated with longer decision times. Statistical analysis (Kendall’s τ > 0.6) revealed strong correlations among perceived safety, trust, and clarity across all conditions. These findings support the potential of LED-based eHMIs - particularly those with full green illumination - to enhance pedestrian safety and decision-making at crossings.
Open Access: Yes
Változások az orvosok, védőnők és egészségügyi szakemberek gyermekvédelmi munkájában, ajánlások a további munkához: Tanulmány a Védőnői Szolgálat 110 éves évfordulója alkalmából
Publication Name: Orvosi Hetilap
Publication Date: 2025-08-31
Volume: 166
Issue: 35
Page Range: 1391-1400
Description:
Introduction: From 13 June 1915, when the National Stefania Association was founded, for almost a century, the health visitors, alongside the doctors, were the health-social-child protection carers of children and families with children, the coordinators of this work. Objective: (1) To review the changes in the last decades that have changed the work of doctors, health visitors and health professionals in child protection; (2) to describe their place and responsibilities in the child protection system; (3) to make suggestions based on our professional experience on how they can work more effectively to better represent the interests of children in need. Method: We studied the legislation, professional regulations and literature related to the topic, and we also carried out systematic and analytical work based on our own professional experience. Results: Act III of 1993 on social welfare, Act XXXI of 1997 on child protection, and the creation of the family and child welfare services and centres in 2016, brought radical changes. Health professionals play a key role in the child protection signalling system and work together with other child protection actors. Our own health-child protection DDTT (Detection–Diagnosis–Treatment–Therapy) model and checklist, which have proved successful in our own work, can be used to help health professionals in their health-child protection work. Discussion: The place and responsibilities of doctors, health visitors and health professionals in the child protection system have become clearer. The role of all health professionals is very important in this work. Conclusion: More attention should be focused on cases within their own competence, on primary prevention in the field of health and child protection. Teamwork, traditionally important in the health sector, is also important in the health and child protection field. Also to follow the changes, participation in training courses is recommended. For more effective work, we recommend the use of the DDTT model and checklist, which have been well proven in our own work in health and child protection. Orv Hetil. 2025; 166(35): 1391–1400.
Open Access: Yes
Technologies for Minimizing Track Degradation and Additional Dynamic Effects at Permanent Way-Railway Bridge Stiffness Transitions †
Publication Name: Engineering Proceedings
Publication Date: 2025-01-01
Volume: 113
Issue: 1
Page Range: Unknown
Description:
Railway tracks at bridge approaches experience significant vertical stiffness transitions, leading to adverse effects such as settlement and increased dynamic loads, accelerating track degradation. This study explores various structural solutions, including geosynthetics, reinforced ballast, transition slabs, under sleeper pads (USPs), under ballast mats (UBMs), jet grouting, and special rail fasteners. Despite their application, these solutions often fail due to their static nature. This paper introduces an adaptive approach using special rail fastenings with real-time adjustable stiffness. This system dynamically modifies rail support characteristics based on train speed and track conditions, improving track durability, ride quality, and maintenance strategies. The findings demonstrate the potential of adaptive systems to enhance railway infrastructure performance.
Open Access: Yes
Bioinformatics analysis of Rickettsia typhi autoimmune associations and screening of Streptomyces-derived inhibitors
Publication Name: Biodata Mining
Publication Date: 2025-12-01
Volume: 18
Issue: 1
Page Range: Unknown
Description:
Background: Rickettsia typhi is the causative agent of epidemic murine typhus and Rocky Mountain spotted fever. The infection can affect multiple vital organs, including the heart, lungs, kidneys, and brain. Doxycycline is the recommended treatment but inflammation, mal-response, and drug resistance may arise. No natural product inhibitors have been reported against this bacterium. Aim: The objective of this study was to establish a potential connection between autoimmune disorders triggered by R. typhi, identify therapeutic targets within its core proteome, and explore novel natural product inhibitors from Streptomyces spp. that could potentially inhibit it. Methodology: Complete proteomes of four publicly available R. typhi strains were used for pan-proteomic analysis. The fni gene product (Isopentenyl pyrophosphate isomerase) was selected as the potential drug target. Molecular docking of 607 Streptomyces-derived metabolites was performed, with top hits validated using DiffDock and Vinardo scoring. Additionally, the Absorption, Distribution, Metabolism, Excretion, and Toxicity properties of the leading compounds were assessed via pkCSM, and formulation characteristics optimized using FormulationAI. Results: Out of the 803 core proteins, associations between 14 proteins were mined for autoimmune diseases (including psoriasis, rheumatoid arthritis, optic atrophy, uveitis, even-plus syndrome, Sjogren syndrome, inflammatory bowel disease, allergic rhinitis, systemic lupus erythematosus, sclerosis, Stevens-Johnson syndrome, toxic epidermal necrolysis, colitis etc.). 17 core proteins were predicted as druggable. ZINC01482946 demonstrated the strongest inhibitory potential, as confirmed by DiffDock scoring, convolutional neural network-based ranking, and Vinardo scoring. It demonstrated a stable configuration and exhibited a favorable pharmacokinetic profile, with bioavailability enhanced through cyclodextrin complexation. Conclusion: To the best of our knowledge, this is the first report identifying human autoimmune associations with R. typhi and natural product inhibitors targeting the pathogen. ZINC01482946 shows potential as an effective inhibitor of R. typhi, while SBE-β-CD appears to be a promising cyclodextrin for improving its solubility and bioavailability. Clinical trial number: Not applicable.
Open Access: Yes
Cognitive-Biased Decision on Courier Express Parcel Market and the Effect of Narratives
Publication Name: Logistics
Publication Date: 2025-03-01
Volume: 9
Issue: 1
Page Range: Unknown
Description:
Background: Extensive research highlights the economic benefits of collaboration among parcel delivery service providers, yet mutually advantageous cooperative arrangements remain limited in Hungary’s online shopping sector. Service providers typically prefer to operate independently rather than cooperate with competitors. However, the COVID-19 pandemic significantly altered industry dynamics, leading to increased collaboration. Methods: Against this backdrop, this study explores two key research questions. First, it examines the role of economic narratives in shaping market dynamics. Second, it investigates the cognitive biases influencing decision-makers during the pandemic, based on an analysis of Hungary’s parcel delivery sector. Semi-structured interviews were conducted with key actors in the logistics industry, and the data were analyzed using abductive thematic analysis. Results: The findings reveal that specific economic narratives, such as those emphasizing efficiency and safety, indirectly influenced market mechanisms during the COVID-19 pandemic. Notably, the shift in consumer demand towards contactless parcel lockers created new incentives for collaboration. Additionally, this study demonstrates that decision-makers exhibited cognitive biases such as risk aversion, which affected their willingness to cooperate. Conclusions: The research concludes that strong economic incentives can override these biases, fostering collaboration among service providers.
Open Access: Yes
Financial Geographic Accessibility and Corporate Innovation: An Analysis of Spatial Synergy Based on Land Use and Environmental Sustainability
Publication Name: Land Degradation and Development
Publication Date: 2025-08-15
Volume: 36
Issue: 13
Page Range: 4562-4587
Description:
In the face of land degradation and environmental constraints, it is imperative to have an adaptive financial geography structure and a land resource utilization system that supports corporate innovation. This study constructs a refined financial geographic accessibility measurement index. By integrating multi-source spatio-temporal big data, the study breaks through the static limitation of traditional statistical data. It accurately analyzes the spatial synergistic effect between the spatial distribution of financial institutions and land use planning. Land use data, such as spatial development rate and spatial interest points, provide high-precision spatial evidence for revealing the mechanism of financial geographic accessibility affecting corporate innovation. Further, from the environmental sustainability perspective, this paper studies the moderating effect of environmental constraints on corporate innovation. Financial geographic accessibility can improve corporate innovation by reducing financing costs, accelerating knowledge spillover, realizing intermediate input sharing, improving labor matching, and giving play to location advantages. Notably, this facilitation effect performs better in cities with high energy consumption and carbon emissions. Heterogeneity analysis shows that proximity to the city center, low industrial maturity, government subsidies, soes, and large-scale corporations significantly amplify the innovation benefits of financial geographic accessibility. This study combines remote sensing data with spatial big data to provide a new methodological framework for analyzing land use and degradation.
Open Access: Yes
DOI: 10.1002/ldr.5653
